顎関節症における塩酸トルペリゾンの投与とＳＳＰ療法の併用に関する臨床的研究

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  • Clinical study on treatment of temporomandibular arthrosis with a combination of tolperisone-HCL and SSP therapy.

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A combination therapy of tolperisone-HCL, a hypomyotonic agent, with SSP was performed in 49 patients with temporomandibular arthrosis excluding those who were caused by overt organic lesion, abnormal occlusion, or prosthesis. This conservative treatment consisted of medication and physiotherapy for relieving pain and myotony, was adopted as a treatment method of our first choice.<BR>Results:<BR>(1) A high improvement rate was obtained in the following symptoms: arthralgia during exercise, autochthonous arthralgia, tenderness in the joint and muscles, trismus and unpleasantness.<BR>(2) The effect was not favorable in patients with simple articular noise.<BR>(3) The treatment was effective on type I arthrosis according to the classification of the Japanese Society for Temporomandibular Joint.<BR>(4) The overall rating of effectiveness was: markedly effective in 16.3 %, effective in 40.8 %, slightly effective in 28.6 %, and no effect in 14.3 %.<BR>(5) Adverse side-effects probably related to the agent adminstered were observed in 6 out of 49 cases (12.2 %). however, these manifestations were all slight in degree, requiring no withdrawal of the drug in all cases.<BR>(6) No side effects probably due to SSP therapy were found. On the basis of these findings, it is considered that the combined administration of tolperisone-HCl as medication and SSP as physiotherapy was effective and highly safe for relieving the symptoms of temporomandibular arthrosis caused by myotony.

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