Omenn症候群患児の臍帯血移植後に発症したMycobacterium avium complex感染症
書誌事項
- タイトル別名
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- Mycobacterium avium Complex Infection after Cord Blood Stem Cell Transplantation in a Patient with Omenn Syndrome
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Omenn Syndrome is a form of severe congenital combined immunodeficiency characterized by erythrodermia, hepatosplenomegaly, lymphadenopathy, and alopecia. Most patients with Omenn Syndrome are threatened due to severe infections; thus, they are generally treated with cord blood or bone marrow stem cell transplantation in early childhood. We here report a patient with Omenn Syndrome who suffered Mycobacterium avium complex (MAC) infection in the neck and axillary lymph nodes after cord blood stem cell transplantation. Thispatient was mainly treated with ethambutol, rifampicin, clarithromycin, and azithromycin, and the repeated incisions and drainages of lymph node lesions were performed for 2 years after the onset of MAC infection. These results suggested that administration of antituberculosis drugs and macrolide antibiotics, and surgical treatment are effective for systemic MAC infections after hematopoietic cell transplantation.
収録刊行物
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- 日本小児血液学会雑誌
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日本小児血液学会雑誌 22 (2), 129-132, 2008
特定非営利活動法人 日本小児血液・がん学会
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詳細情報 詳細情報について
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- CRID
- 1390282679318813568
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- NII論文ID
- 130004345980
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- ISSN
- 18844723
- 09138706
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可