小児Ｋｉ‐１　ｌｙｍｐｈｏｍａの２例　小児報告例の検討を含めて

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タイトル別名
  • Childhood Ki-1 lymphoma. Case Reports and a Review of the Literature.
  • Case Reports and a Review of the Literature
  • 小児報告例の検討を含めて

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Two cases with childhood Ki-1 lymphoma were reported in this paper. An eight-year-old female (Case 1) had a stage III lymphoma of tracheo-bronchial origin. She had a resection of the tumor, chemotherapy for 3 years and survived for 6 years. A six-year-old female (Case 2) had an abdominal lymphoma also involving mediastinum and cervical lymph nodes (stage III). She had a biopsy of the tumor, chemotherapy for 3 years and survived for 4 years and 7 months. These cases were diagnosed as malignant lymphoma (diffuse, large cell type in the LSG classification) that also had the histologic characteristics of an anaplastic large cell lymphoma, positivity for Ki-1 antigen (CD30), and no specific cell marker. So far, thirty-eight cases of childhood Ki-1 lymphoma have been reported in the literature. Clinical findings indicate they have a high occurrence rate in the older child, skin involvement (one third of the cases), good response to chemotherapy and a favorable prognosis.

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