成熟か牛構成細胞における細胞動態　ＩＩＩ　　ナイトロミン負荷か牛における細胞動態の検討

• 村上 匡孝

  松下記念病院耳鼻咽喉科 京都府立医科大学耳鼻咽喉科

• 安田 範夫

  国立舞鶴病院耳鼻咽喉科 京都府立医科大学耳鼻咽喉科

• 橘 正芳

  京都府立医科大学耳鼻咽喉科

• 水越 治

  京都府立医科大学耳鼻咽喉科

書誌事項

タイトル別名

• Cell kinetics of the component cells of mature cochlea. (3rd Report).
• ナイトロミン負荷蝸牛における細胞動態の検討

抄録

By ³H-thymidine autoradiography in the cochlea of the normal adult mice, we have previously shown that (1) DNA synthesis occurs in the intermediate cells in the stria vascularis, mesothelial cells in the Reissner's membrane, epithelial cells in the basilar membrane, and cells in the spiral ligament (2) The basilar membrane has the shortest cell cycle (3) DNA synthesis does not occur in the supporting cells of the organ of Corti. In this study, we carried out the same autoradiography after injection of nitrogen mustard-N-oxide (NMO), which damages the outer hair cells. A few grains were detected in some supporting cells of organ of Corti and mitosis was seen in Claudius' cells. The labeling indexes of supporting cells, basilar epithels, and mesothelial cells of Reissner's membrane increased dose-dependently with injection of NMO, although that of stria vascularis was not affected by the dose.

収録刊行物

• Ｅａｒ　Ｒｅｓｅａｒｃｈ　Ｊａｐａｎ

  Ｅａｒ　Ｒｅｓｅａｒｃｈ　Ｊａｐａｎ 19 10-12, 1988

  日本耳科学会

詳細情報

• CRID: 1390282679747581696
• NII論文ID: 130004355764
• DOI: 10.11289/otoljpn1981.19.10
• ISSN: 18845797
• ISSN: 02889781
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可