白色便性下痢 (仮性小児コレラ) 患児の病原検索成績特にブドウ球菌分離について

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  • Studies on the Pathogenic Agent of Infantile Diarrhea Accompanied by Watery and White Colored Stool (Pseudocholera inf antum), Particularly on the Isolation of Staphylococci

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An epidemic infantile diarrhea characterized by watery and white colored stool occurred among milk infants in Takaoka City of Toyama prefecture during the period from January to February 1962. Stools of nine patients were examined virologically and bacteriologically.<BR>1) No virus was isolated by the use of MK cell and HeLa cell. On the other hand, by the aerobic bactriological examination with SS, BTB and agar plate containing rabbit blood, known intestinal pathogenic bacteria and streptococci were not isolated.<BR>2) Staphylococci were isolated from four typical white colored stools by using No.110 and PP plate which were specially used for isolation of staphylococci. All these strains had the nature of pathogenic strain.<BR>3) All the isolated strains were proved to be resistant against penicilline, highly sensitive against streptomycine and chloramphenicol, and sensitive against tetracycline and erythromycine. These strains were proved to be more resistant against sublimate than the control strain.<BR>4) By the phage typing test, all the strains had the same pattern of 80/81/KS6 includ - ing 80 and 81 phage as the hospital staphylococci.<BR>5) From these results of the determination, staphylococci as well as virus must be recognized as the causative agent of watery and white colored diarrhea, Pseudocholera infantum.

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