腎スキャニング剤としての<SUP>99<I>m</I></SUP>Tc-DMSに関する基礎的検討

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  • Evaluation of <SUP>99<I>m</I></SUP>Tc-DMS Complex as Renal Scanning Agent
  • ジン スキャニングザイ トシテノ 99m Tc DMS ニ カンスル キソテキ

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A simple kit for the preparation of 99mTc-labeled dimercaptosuccinate in a lyophilized form is described. The kit provides consistent more than 80% yields of the complex hawing the kidney seeking properties. The distribution of the complex was performed in the human by blood clearance, external renal measurements and scintillation camera imaging. Radiation dose based on the organ distribution in human was calculated, and the dose of whole body, kidney, testes and ovaries was 18.7 mrad/mCi, 674 mrad/ mCi, 14.5 mrad/mCi and 20.6 mrad/mCi, respectively.

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