In vivoけい光X線分析法による甲状腺のヨウ素濃度の測定

今村 恵子, 佐々木 康人, 宇治 輝幸, 染谷 一彦, 藤井 正道

doi:10.3769/radioisotopes.26.12_858

In vivoけい光X線分析法による甲状腺のヨウ素濃度の測定

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今村恵子

聖マリアンナ医科大学放射線医学教室
佐々木康人

聖マリアンナ医科大学第3内科学教室
宇治輝幸

聖マリアンナ医科大学放射線医学教室
染谷一彦

聖マリアンナ医科大学第3内科学教室
藤井正道

聖マリアンナ医科大学放射線医学教室

書誌事項

タイトル別名

In vivo X-ray Fluorescent Analysis of lodine Concentration in the Thyroid
In vivo ケイコウ Xセンブンセキホウニヨルコウジョウセンノヨ

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抄録

A simple apparatus was made for the X-ray fluorescent anlaysis of iodine concentration of the thyroid. The apparatus consists of ²⁴¹Am γ-ray source of 300mCi and pure Ge detector of 50mm²×5mm. Diverging collimator was designed to achieve a full view of the thyroid. The detectable concentration was 0.2mg iodine/g tissue assuming the coefficient of variance of 30% and the counting time of 5 minutes. Measurement was performed for autopsied 10 thyroids and the results were in good correlation with those by neutron activation analysis (r=0.93) . Iodine concentration ranged 0.3-1.2mg/g (mean 0.6mg/g) and compared well with the data in literatures. This technique is useful for the in vivo measurement of thyroidal iodine content in patients.