形状記憶合金による代用耳小骨に関する研究

DOI
  • 江夏 国寿
    Department of Otorhinolaryngology, Miyazaki Medical College

書誌事項

タイトル別名
  • Utilization of Ni-Ti Shape Memory Alloy for Ossicular Prosthesis and Its Biocompatibility with the Incus of Cats

抄録

Several types of ossicular prosthesis have been used for surgery of the conductive deafness with a ossicular deficit or fixation. Even the experienced otological surgeons, however, feel a difficulty in fixing the prosthesis because of a deep and limited surgical field. Although surgical procedures are carried out carefully under a operating microscope, there are many reports of cases whose prostheses are slipped out or whose ossicles are eroded by the tightly fitted prosthesis. In this study, a new type of prosthesis was developed using shape memory alloy, and its biocompatibility with the long crus of the incus was examined in cats. The prosthesis was made with Ni-Ti shape memory alloy wire (Tohokukinzoku Co. V-4332, As point of 33° and diameter of 0.1mm) by twining around a mold and placing in a 500° vacuum furnance for 60min for a memory treatment. Before surgical use, the prosthesis was stretched in ice water. Implantation of the prosthesis was performed in ten cats (20 ears). The stretched prosthesis could be twined easily and securely around the long crus of the incus by warming with water of 45°. The biocompatibility of the implanted prosthesis onto the incus was examined 62 to 262 days after the operation. All prosthesis were found to exist at the implanted position twining firmly around the incus. In 70% ears, however, deformities of the long crus of the incus were observed with the histological finding of bone absorption. Examinations of the surface of the prosthesis with SEM and x-ray microanalyzer revealed Ni in the shape memoey alloy melted out into the surrounding tissues. From these results, it is concluded that the ossicular prosthesis using Ni-Ti alloy can relieve the difficulty in fitting it to the ossicle, but some surface treatment or coating is necessary for clinical use because of the toxic effect of Ni melting from the prosthesis on the incus.

収録刊行物

詳細情報 詳細情報について

  • CRID
    1390282680476036352
  • NII論文ID
    130004403137
  • DOI
    10.11334/jibi1954.32.2_256
  • ISSN
    04477227
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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