鼻疾患におけるα-キモトリプシンの臨床的応用

DOI
  • 浅井 栄暢
    Department of Oto-Rhino-Laryngology, Medical School of Kumamoto University
  • 上野 敬之
    Department of Oto-Rhino-Laryngology, Medical School of Kumamoto University
  • 金子 宣恒
    Department of Oto-Rhino-Laryngology, Medical School of Kumamoto University

書誌事項

タイトル別名
  • Clinical Application of Alpha-chymotrypsin to Rhinological Disease

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抄録

Alpha-chym.otrypsin, a kind of the enzyme abstracted from pancreas of the mammal, has fiblinolytic agent, anti-inflammatory agent and anti-edematous agent.<BR>The authors used this enzym-solution to treat some kinds of the chronic inflammatory disease in rhinological field by nasal-rinsing or spraying, and to treat or prevent from buccal swelling after radical operation of sinuitis maxillaris et ethmoidalis chronica by intramuscular injection.<BR>The results obtained are as follows<BR>Of 15 cases of rhinitis chronica hyperplastica et simplex, 4 cases were affected remarkably well, 8 cases well and 3 cases a little well, while 2 cases were affected well, and 3 cases a little well of 5 cases of rhinitis chronica atrophica. Conservative treatment with this enzyme on 11 cases of sinuitis and postoperative sinuitis m.axillaris chronica had the best effects on 4 cases, better effects on 4 cases, a little good effect on 2 cases and no effect on a case.<BR>Buccal swelling after radical operation of sinuitis responded to intramuscular injection of this enzyme-solution well, but blooding-tendency during operation a little incresed.

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