Quantification of Antioxidants by Using Chlorpromazine Hydrochloride: Application of the Method to Food and Medicinal Plant Samples
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- NAGARAJA Padmarajaiah
- Department of Studies in Chemistry, University of Mysore
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- ARADHANA Narayanan
- Department of Studies in Chemistry, University of Mysore
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- SUMA Aandamurthy
- Department of Studies in Chemistry, University of Mysore
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- SHIVAKUMAR Anantharaman
- Department of Studies in Chemistry, University of Mysore
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- CHAMARAJA Nelligere Arkeshwaraiah
- Department of Studies in Chemistry, University of Mysore
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Chlorpromazine hydrochloride (CPH) (3-(2-chloro-phenothiazine-10-yl)-propyl] dimethylamine hydrochloride) has been the subject of a large number of studies employing a broad spectrum of oxidants, and chosen to examine the course of electron transfer reactions. We report on a method to determine the antioxidant activity of some food and medicinal plants using the oxidation of CPH by chromium(VI) to form a stable CPH radical in the 1:1 orthophosphoric acid–ethyl alcohol (OPA-EtOH) medium. The pink color of the control solution was measured at λmax of 530 nm. Nine standard antioxidants have been studied by this method, along with the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The EC50, TEC50, antioxidant efficacy and the stoichiometric values for antioxidants have been evaluated. The radical scavenging activity expressed as EC50 ranged from 9.2 μg/mL in Camellia sinensis to 448.18 μg/mL in Cuminum cyminum. The application of a simple and versatile antioxidant capacity assay for dietary polyphenols and medicinal plant extracts, which are commonly used in Ayurveda opens its relevance in the field of antioxidant analysis.
収録刊行物
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- Analytical Sciences
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Analytical Sciences 30 (2), 251-256, 2014
社団法人 日本分析化学会
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詳細情報 詳細情報について
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- CRID
- 1390282679238196480
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- NII論文ID
- 130004442261
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- NII書誌ID
- AA10500785
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- COI
- 1:STN:280:DC%2BC2cvkslaisg%3D%3D
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- ISSN
- 13482246
- 09106340
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- NDL書誌ID
- 025287282
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- PubMed
- 24521912
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- Web Site
- https://ndlsearch.ndl.go.jp/books/R000000004-I025287282
- https://link.springer.com/content/pdf/10.2116/analsci.30.251.pdf
- https://link.springer.com/article/10.2116/analsci.30.251/fulltext.html
- https://www.jstage.jst.go.jp/article/analsci/30/2/30_251/_pdf
- https://search.jamas.or.jp/link/ui/2015061523
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
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