Anti-obesity effects of traditional and standardized meju in high-fat diet-induced obese C57BL/6J mice
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- Bae Cho-Rong
- Department of Food Science and Human Nutrition, and Research Institute of Humans Ecology, Chonbuk National University
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- Kwon Dae-Young
- Korea Food Research Division, Korea Food Research Institute
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- Cha Youn-Soo
- Department of Food Science and Human Nutrition, and Research Institute of Humans Ecology, Chonbuk National University
書誌事項
- タイトル別名
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- Anti-obesity effects of traditional and standardized <i>meju</i> in high-fat diet-induced obese C57BL/6J mice
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抄録
The aim of the study was to evaluate the anti-obesity effects of two types of meju in diet induced obese C57BL/6J mice. Animals were randomly divided into 4 dietary group (n = 10); normal diet, high fat diet with 30% soybean, high fat diet with 30% traditional meju, high fat diet with 30% standardized meju. After 16 weeks, after animals were sacrificed. It was observed that the high fat diet with 30% traditional meju and high fat diet with 30% standardized meju significantly reduced body weight gain, epididymal fat weight, serum triglyceride along with serum insulin and leptin levels compared to the high fat diet with 30% soybean. And also, the expression levels of hepatic lipid anabolic genes were significantly decreased in the high fat diet with 30% traditional meju and high fat diet with 30% standardized meju compared to the high fat diet with 30% soybean. In conclusion, the assessment of all the obesity markers strongly advocate the anti-obesity effect of traditional as well as standardized meju in diet induce obesity conditions.
収録刊行物
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- Journal of Clinical Biochemistry and Nutrition
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Journal of Clinical Biochemistry and Nutrition 54 (1), 45-50, 2014
一般社団法人 日本酸化ストレス学会