Infiltration of Scars in Sarcoidosis

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  • サルコイドーシスにおける瘢痕浸潤について
  • サルコイドーシス ニ オケル ハンコン シンジュン ニ ツイテ
  • サルコイドーシスにおけるはんこん浸潤について

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Abstract

Of 179 patients with sarcoidosis observed in the Dermatology Departments of both Kanazawa University and Kanazawa Medical University for the period of 21 years from 1960 to 1981, 34 patients (19%) were found to have infiltration of old-standing scars most often on the knees, followed by the elbows and others. In biopsy specimens, groups of small epithelioid granulomas containing glass-like foreign bodies and fibrosis surrounding the granulomas were seen under the atrophic epidermis. By electron microscopy, the granulomas were revealed to be composed of epithelioid cells of following three types: (1) the cells containing a number of lysosome-like dense bodies in the cytoplasm, (2) those showing numerous cytoplasmic vacuoles and (3) those having a lot of residual bodies and myelin figures within the cytoplasm.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 43 (Suppl), 1085-1099, 1981

    Western Division of Japanese Dermatological Association

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