Lipogranuloma arising in the collapsed mucous cyst of the lower lip following Castor oil application

  • Takamori Kazunori
    Division of Pediatric Dentistry, Department of Human Development and Fostering, Meikai University School of Dentistry
  • Tajima Yoshifumi
    Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
  • Okazawa Jiroh
    Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
  • Kusama Kaoru
    Division of Pathology, Department of Diagnostic and Therapeutic Sciences, Meikai University School of Dentistry
  • Watanabe Shigeru
    Division of Pediatric Dentistry, Department of Human Development and Fostering, Meikai University School of Dentistry

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This report presents a case of Lipogranuloma of lower lip in an 8-year-old boy. The patient has been noticed a painless swelling on his lower lip for about three months. He had a past history of repeated rupture of the lesion, and the lesion currently presented with a soft and nodular mass at the left lower lip. The clinical diagnosis was lipoma. Histopathological examination of the surgically removed specimen revealed a number of fat-like globular material infiltrating into the submucosal tissues including skeletal muscle and atrophic minor salivary gland. A granulomatous inflammation with macrophages was noted over the lipidic infiltration, leading to a final diagnosis of ‘lipogranuloma of foreign body type arising in collapsed mucous cyst’. The lesion was induced by repeating administration of Castor oil on the collapsed mucous cyst in the region. In the present report, we describe a case of lipogranuloma arising in the collapsed mucous cyst caused by Castor oil application, which were very rare of maxillofacial region.

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