Air Pollution with Particulate Matter and Mutagens: Relevance of Asian Dust to Mutagenicity of Airborne Particles in Japan

• Watanabe Tetsushi

  Kyoto Pharmaceutical University

• Hasei Tomohiro

  Kyoto Pharmaceutical University

• Kokunai Osamu

  Kyoto Pharmaceutical University

• Coulibaly Souleymane

  Kyoto Pharmaceutical University

• Nishimura Sachi

  Kyoto Pharmaceutical University

• Fukasawa Moe

  Kyoto Pharmaceutical University

• Takahashi Ryohei

  Kyoto Pharmaceutical University

• Mori Yasuko

  Kyoto Pharmaceutical University

• Fujita Kosuke

  Kyoto Pharmaceutical University

• Yoshihara Yuri

  Kyoto Pharmaceutical University

• Miyake Yumi

  Kyoto Pharmaceutical University

• Kishi Akane

  Kyoto Pharmaceutical University

• Matsui Motoki

  Kyoto Pharmaceutical University

• Ikemori Fumikazu

  Nagoya City Institute of Environmental Science

• Funasaka Kunihiro

  Osaka City Institute of Public Health and Environmental Science

• Toriba Akira

  Kanazawa University

• Hayakawa Kazuichi

  Kanazawa University

• Arashidani Kei-ichi

  University of Occupational and Environmental Health

• Inaba Yohei

  National Institute of Public Health

• Sera Nobuyuki

  Fukuoka Institute of Health Environmental Science

• Deguchi Yuya

  Nagasaki International University

• Seiyama Tetsurou

  Tottori Prefectural Institute of Public Health and Environmental Science

• Yamaguchi Takako

  Kobe Gakuin University

• Watanabe Masanari

  Tottori University

• Honda Naoko

  Kyoto Pharmaceutical University Sonoda Women's University

• Wakabayashi Keiji

  Kyoto Pharmaceutical University University of Shizuoka

• Totsuka Yukari

  National Cancer Center

Abstract

To reveal the contamination levels of ambient air with particulate matter and mutagens in Japan and the influence of their long-range transport from the Asian continent, we collected airborne particles at 10 sites, from rural sites to metropolitan areas, in central and western areas of Japan for a year, from July 2008 to June 2009. The fluctuation patterns and levels of airborne particle concentration were similar among the 10 sites, and remarkable increases of the concentrations were seen on a few sampling dates, including March 16 and 17, 2009. Most airborne particles collected at the 10 sites showed mutagenicity toward Salmonella typhimurium YG1024 without a mammalian metabolic system (S9 mix) in the Ames test. The mutagenicity levels were quite different among the sampling sites, and the levels seemed to be dependent on the extent of urbanization and industrialization of the subject areas. At Yurihama, a rural site on the west coast of Japan, the mutagenicity level of airborne particles was low, but the particles collected on March 16 and 17, 2009, showed relatively high mutagenicity, >40 revertants/m³, in YG1024 without S9 mix. Airborne particles collected on March 16 and 17, 2009, at most sites showed relatively high or high mutagenicity, >80 revertants/m³, in YG1024 without S9 mix. High coefficients of correlation were found between the concentration and mutagenicity of airborne particles collected in spring, from March to May, for many sites. The results of back trajectory analysis indicated that air masses for March 16 and 17, 2009, had moved from the Asian continent to Japan. The arrival of Asian dust in central and western areas of Japan on those days was reported by the Japan Meteorological Agency. These results suggest that the arrival of mutagens accompanied by Asian dust could be evidently found at Yurihama on March 2009.<br>

Journal

• Genes and Environment

  Genes and Environment 36 (3), 120-136, 2014

  The Japanese Environmental Mutagen Society

Keywords

• ambient air
• suspended particle
• Japan
• Asian dust
• Ames test

Details

• CRID: 1390001205257848192
• NII Article ID: 130004481217
• NII Book ID: AA1212552X
• DOI: 10.3123/jemsge.2014.013
• ISSN: 18807062
• ISSN: 18807046
• NDL BIB ID: 025704331
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I025704331
• Web Site: https://search.jamas.or.jp/link/ui/2015244719
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed