書誌事項
- タイトル別名
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- A Consumption Coagulopathy in an Infant with Hemolytic-Uremic Syndrome.
- ショウモウセイ ギョウコ ショウガイショウ ノ ゾウ オ テイシタ ヨウケツセイ ニョウドクショウ ショウコウグン ノ 1 ニュウジレイ
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抄録
A report was made of a case of the hemolytic-uremic syndrome associated with consumption coagulopathy in a 2-month-old female infant.<br>After a week's duration of fever and diarrhea, the patient rapidly developed pallor, petechial hemorrhages and edema.<br>On admission, she was anemic with a slight jaundice. The liver was 6 cm and the spleen 4 cm palpable,<br>The hematologic examination showed RBC 3.46×106/mm3, Hb 8.8g/100ml, WBC 2,100/mm3. platelets 60,000/mm3 and reticulocytes 5‰. Peripheral blood smears levealed a marked anisocitosis, poikilocytosis and fragmented erythrocytes. Blood culture was negative, so was Coombs test. The direct serum bilirubin level was 0.9mg/100ml and indirect 1.4mg/100ml. The BUM level was 30mg/100ml. The albumin in urine was 2 plus. The bleeding time was over 30 minutes. Bleeding occurred from venipuncture sites and ear lobe.<br>A coagulation study revealed a marked prolonged clotting time, recalcification time, prothrombin time, kaolin partial thromboplastin time and thrombin time. The factor I level was 10mg/100ml. Levels of factors V and VIII were 36% and 28%, respectively. A moderate decrease was also found in factors II, VII, IX and X. No abnormal fibrinolysis was observed.<br>Despite a replacement thrapy of clotting factors and heparin adminstration, levels of factors I, II, VII, IX and X failed to increase on the fifth hospital day. The child died on the seventh hospital day. No autopsy was performed.
収録刊行物
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- 臨床血液
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臨床血液 15 (10), 1133-1141, 1974
一般社団法人 日本血液学会
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詳細情報 詳細情報について
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- CRID
- 1390282680009231872
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- NII論文ID
- 130004497613
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- NII書誌ID
- AN00252940
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- COI
- 1:STN:280:CSqC3MjgslY%3D
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- ISSN
- 18820824
- 04851439
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- NDL書誌ID
- 7656766
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- PubMed
- 4476810
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可