Purpura hyperglobulinemicaの2症例

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  • 丸尾 國造
    県西部浜松医療センター消化器科（元，県西部浜松医療センター血液内科）
  • 吉川 治哉
    名古屋第一赤十字病院内科（元，県西部浜松医療センター血液内科）

書誌事項

タイトル別名
  • Two Cases of Purpura Hyperglobulinemica
  • Purpura hyperglobulinemica ノ 2 ショウレイ

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抄録

Two cases of purpura hyperglobulinemica were observed. The first case, 30-year-old female, presented purpura on the both lower extremities and diffuse swelling of the left parotid gland with normal salivary excretion. The second case, 27-year-old female, presented purpura on both legs after longtime standing. Both cases showed accelerated erythrocyte sedimentation rate, polyclonal hypergammaglobulinemia (31.4% and 36.4%), positive RA test and positive anti-platelet antibody by indirect Coombs' consumption test.<br>Besides, the second case revealed positive anti-nuclear factor (speckled pattern) and decrease of values of C4 and C3C, however, since renal biopsy disclosed no deposit of immunoglobulin nor complement, the diagnosis as SLE was excluded. Administration of prednisolone brought good clinical effects and reappearance of purpura was hardly seen even after provocation in both cases.<br>It would be suggested that purpura hyperglobulinemica is a prodromal or partial symptom of collagen disease, therefore, the careful follow-up study should be needed.

収録刊行物

  • 臨床血液

    臨床血液 21 (8), 1209-1216, 1980

    一般社団法人 日本血液学会

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