A Case of Diabetic Foot Infection with Daptomycin-induced Acute Eosinophilic Pneumonia

DOI Web Site
  • Murakami Takaaki
    Department of Diabetes Mellitus and Endocrinology, Osaka Red Cross Hospital
  • Koyama Taiji
    Department of Otolaryngology - Head and Neck Surgery, Osaka Red Cross Hospital
  • Masui Hideyuki
    Department of Diabetes Mellitus and Endocrinology, Osaka Red Cross Hospital
  • Hatoko Tomonobu
    Department of Diabetes Mellitus and Endocrinology, Osaka Red Cross Hospital
  • Shimamura Kiyotaka
    Department of Diabetes Mellitus and Endocrinology, Osaka Red Cross Hospital
  • Matsuda Yuki
    Department of Diabetes Mellitus and Endocrinology, Osaka Red Cross Hospital
  • Matsuo Koji
    Department of Diabetes Mellitus and Endocrinology, Osaka Red Cross Hospital
  • Nambu Takuo
    Department of Diabetes Mellitus and Endocrinology, Osaka Red Cross Hospital
  • Yonemitsu Shin
    Department of Diabetes Mellitus and Endocrinology, Osaka Red Cross Hospital
  • Muro Seiji
    Department of Diabetes Mellitus and Endocrinology, Osaka Red Cross Hospital
  • Oki Shogo
    Department of Diabetes Mellitus and Endocrinology, Osaka Red Cross Hospital

Bibliographic Information

Other Title
  • ダプトマイシンによる急性好酸球性肺炎が疑われた糖尿病性足病変に伴う下腿蜂窩織炎の1例
  • 症例報告 ダプトマイシンによる急性好酸球性肺炎が疑われた糖尿病性足病変に伴う下腿蜂窩織炎の1例
  • ショウレイ ホウコク ダプトマイシン ニ ヨル キュウセイ コウサンキュウセイ ハイエン ガ ウタガワレタ トウニョウビョウセイ ソク ビョウヘン ニ トモナウ カタイ ホウカシキエン ノ 1レイ

Search this article

Abstract

A 56-year-old female with a six-year history of poorly controlled diabetes mellitus was admitted for septic shock with infectious diabetic foot ulcers. She was treated with antimicrobial agents, including daptomycin. Although her condition improved, she developed dyspnea and hypoxemia with bilateral pulmonary infiltrates one week after admission. She also exhibited eosinophilia and eosinophil-rich sputum. Her condition rapidly improved following the discontinuation of daptomycin. Therefore, the features of this case were consistent with a diagnosis of daptomycin-induced acute eosinophilic pneumonia. Daptomycin is a relatively new antimicrobial agent whose high degree of efficacy for diabetic skin and soft tissue infections and bacteremia has been proven in clinical trials. Increased attention should be paid to the rare but serious adverse effect of daptomycin-induced acute eosinophilic pneumonia.

Journal

Keywords

Details 詳細情報について

Report a problem

Back to top