脳卒中治療におけるPK/PD PETマイクロドーズパッケージ

• 下瀬川 恵久

  大阪大学大学院医学系研究科核医学講座

• 畑澤 順

  大阪大学大学院医学系研究科核医学講座

書誌事項

タイトル別名

• PK/PD PET micro-dose package in the therapy of the cerebrovascular disease

抄録

Nuclear medicine methodology is one of the powerful tools in evaluating effectiveness and pharmacological analysis of the medical drugs. In the field of the brain disease, evaluation by positron emission tomography (PET) has been established not only in the drug effectiveness test, but also in the whole body pharmacokinetics (PK) and pharmacodynamics (PD) of the drug itself. In this article, we described the present kinetic evaluation of drug effect by PET, especially focusing cerebrovascular disease. We also reported the trend of PET micro-dose test in the process of the recent drug research and development, with introducing the system of the PK/PD PET micro-dose package in our institute.

収録刊行物

• 脳卒中

  脳卒中 35 (2), 147-152, 2013

  一般社団法人 日本脳卒中学会

キーワード

• PET
• micro-dose
• pharmacokinetics
• pharmacodynamics

詳細情報

• CRID: 1390001204638467072
• NII論文ID: 130004543283
• DOI: 10.3995/jstroke.35.147
• ISSN: 18831923
• ISSN: 09120726
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可