Acute Effects of Caffeine Administration on the Ultrastructure of the Golden Hamster Parathyroid Gland

• JAMALI Marjan

  Department of Anatomy, Gifu University, School of Medicine

• HAYAKAWA Daisuke

  Department of Anatomy, Gifu University, School of Medicine

• CHEN Huayue

  Department of Anatomy, Gifu University, School of Medicine

• OZAWA Yuki

  Department of Anatomy, Gifu University, School of Medicine

• TAGUCHI Hirotaka

  Department of Anatomy, Gifu University, School of Medicine

• YANO Ryuichiro

  Department of Anatomy, Gifu University, School of Medicine

• EMURA Shoichi

  College of Medical Sciences, Gifu University

• SHOUMURA Shizuko

  Department of Anatomy, Gifu University, School of Medicine

抄録

This study was conducted to evaluate the acute effects of caffeine on the ultrastructure of the parathyroid glands in golden hamsters. Caffeine was given orally at either 2.5 mg (low dose) or 10 mg (high dose) per 100 g body weight. Caffeine caused a dose dependent decrease of the serum calcium level 2 hours after administration. Transmission electron microscopy of the parathyroid gland revealed that the volume densities occupied by the Golgi complexes and rough endoplasmic reticulum (RER) were found significantly higher 2 hours after receiving high dose of caffeine. Statistical analysis revealed no significant differences regarding to the bone mineral content (BMC) and bone mineral density (BMD).<BR>It is considered that the synthesis of parathyroid hormone is stimulated following caffeine administration.

収録刊行物

• Okajimas Folia Anatomica Japonica

  Okajimas Folia Anatomica Japonica 77 (2-3), 53-57, 2000

  Editorial Board of Okajimas Folia Anatomica Japonica

キーワード

• Caffeine
• Hamster
• Parathyroid
• Ultrastructure

詳細情報

• CRID: 1390282680436718080
• NII論文ID: 130004650542
• DOI: 10.2535/ofaj1936.77.2-3_53
• COI: 1:CAS:528:DC%2BD3cXnvVeqsbY%3D
• ISSN: 0030154X
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可