Evaluation of Neutrophil Function during Hemodialysis Treatment in Healthy Dogs under Anesthesia with Sevoflurane
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- SHIMAMURA Shunsuke
- Cooperative Department of Veterinary Clinical Medicine, Iwate University, Morioka, Iwate 020–8550, Japan
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- KIMURA Ken
- Cooperative Department of Veterinary Clinical Medicine, Iwate University, Morioka, Iwate 020–8550, Japan
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- KATAYAMA Masaaki
- Cooperative Department of Veterinary Clinical Medicine, Iwate University, Morioka, Iwate 020–8550, Japan
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- MASHITA Tadahisa
- Maizuru Animal Medical Center, Maizuru, Kyoto 625–0037, Japan
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- MAEDA Kenichi
- Cooperative Department of Veterinary Clinical Medicine, Kitasato University, Towada, Aomori 034–8628, Japan
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- KOBAYASHI Saori
- Cooperative Department of Veterinary Clinical Medicine, Iwate University, Morioka, Iwate 020–8550, Japan
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- SATO Reeko
- Cooperative Department of Veterinary Clinical Medicine, Iwate University, Morioka, Iwate 020–8550, Japan
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- YASUDA Jun
- Cooperative Department of Veterinary Clinical Medicine, Iwate University, Morioka, Iwate 020–8550, Japan
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抄録
This study evaluated the number and function of neutrophils during 3 hr of hemodialysis in healthy dogs under anesthesia. Isolated neutrophils were used to assess neutrophil adhesion, phagocytosis and the oxidative burst. At 0.5 and 3 hr after the start of hemodialysis treatment, there was a decrease in neutrophil number. The phagocytic ability of neutrophils was decreased 3 hr after the start of hemodialysis. In conclusion, this study demonstrated that hemodialysis reduces the number and phagocytic ability of neutrophils during treatment. However, these changes recover within 24 hr of hemodialysis.
収録刊行物
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- Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ
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Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ 76 (11), 1539-1543, 2014
公益社団法人 日本獣医学会