日本人における組織学的耳硬化症の研究

DOI 被引用文献1件

書誌事項

タイトル別名
  • Temporal Bone Pathology of Japanese Otosclerosis

この論文をさがす

抄録

Five hundred and forty five temporal bones from 273 individuals were studied histopathologically, to clarify the activity, gender ratio, predilection site and incide nce of otosclerosis among Japanese. The relation between otosclerosis and fissula ante fenestram or constituents in the area anterior to the oval window was also studied. Individua ls ranged in age from 6 to 89 y ears.<BR>1) Histological evidence of otosclerotic foci was found in 12 ears,10 individuals; 6 of 172males (7 of 344 ears) and 4 of 101 females (5 o f 201 ears) aged 48 to 84 years; all cases sho wed histologic otosclerosis without clinical otologic symptoms. The prevalence of histologic otosclerosis was calcul ated as 3.66% by individuals and 2.20%by ears. Females were not significantly predominant statistically. Unilaterality wa s 80%(8 of 10 individuals).<BR>2) The most frequent site of otosclerotic foci from data in this study conbined with that from reports published in Japan was the area anterior to the oval window in 52% of the cases. The percentage was about half that in Caucasians.<BR>3) The volume of the otosclerotic foci in the area anterior to the oval window was measured in 6 ears by three-dimensional computer graphic reconstruction. Volume rang ed from 0.079 to 4.023 mm3. In five ears, volume was less than 1 mm3.<BR>4) Otosclerotic foci involved in the area anterior to the oval window were separated from the fissula ante fenestram, but involved the tympanic side of the fissula ante fenestram. It was considered that otosclerosis might arise not from the fissula ante fenestram, but from the area on the tympanic side of the fissula ante fenestram.<BR>5) In the area anterior to the oval window, there were some constituents such as cartilage, new bone, adipose tissue and connective tissue. However, in the ear involving oto sclerosis in the area anterior to the oval window, these constituents were not observed. O tosclerosis may have no relation to these constituents.<BR>6) The lower incidence of clinical otosclerosis among Japanese compared to that among Caucasians was considered due to:<BR>1. the low prevalence of otosclerosis<BR>2. low activity<BR>3. the low rate of involvement of the area anterior to the oval window that causes earlier impaired hearing.

収録刊行物

被引用文献 (1)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ