Lung <i>Nocardia elegans</i> Infection Diagnosed on Matrix-assisted Laser Desorption Ionization-time of Flight Mass Spectrometry (MALDI-TOF MS)

  • Ooi Yukimasa
    Infection Control Office, Osaka Medical College Hospital, Japan
  • Shiba Hideyuki
    Division of Rheumatology, Osaka Medical College Hospital, Japan Department of the First Internal Medicine, Osaka Medical College, Japan
  • Nagai Koji
    Division of Rheumatology, Osaka Medical College Hospital, Japan Department of the First Internal Medicine, Osaka Medical College, Japan
  • Higashiyama Tomohiro
    Department of Clinical and Labolatory Medicine, Osaka Medical College, Japan
  • Nakanishi Toyofumi
    Department of Clinical and Labolatory Medicine, Osaka Medical College, Japan
  • Nakano Takashi
    Infection Control Office, Osaka Medical College Hospital, Japan
  • Ukimura Akira
    Infection Control Office, Osaka Medical College Hospital, Japan
  • Gonoi Tohru
    Medical Mycology Research Center, Chiba University, Japan

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抄録

A 73-year-old man with adultonset Still's disease developed a high fever, coughing, dyspnea and bloody sputum and was therefore admitted to our hospital. Thoracic X-ray and CT scans revealed oval lesions in the bilateral lungs. A bacterial isolate from the sputum was identified to be Nocardia elegans (N. elegans) on comparative 16S rRNA gene sequencing and Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS). The patient recovered following treatment with imipenem/cilastatin and amikacin. To the best of our knowledge, this is the first case of nocardiosis caused by N. elegans identified on MALDI-TOF MS.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 53 (18), 2111-2113, 2014

    一般社団法人 日本内科学会

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