Ex vivo efficacy evaluation of laser vaporization for treatment of benign prostatic hyperplasia using a 300-W high-power laser diode with a wavelength of 980 nm

• Takada Junya

  Graduate School of Engineering, Osaka University

• Honda Norihiro

  Institute for Academic Initiatives, Osaka University

• Hazama Hisanao

  Graduate School of Engineering, Osaka University

• Awazu Kunio

  Graduate School of Engineering, Osaka University Graduate School of Frontier Biosciences, Osaka University The Center for Advanced Medical Engineering and Informatics, Osaka University

書誌事項

タイトル別名

• <i>Ex vivo</i> efficacy evaluation of laser vaporization for treatment of benign prostatic hyperplasia using a 300-W high-power laser diode with a wavelength of 980 nm

抄録

Background and Objective: Laser vaporization of the prostate is considered to be a promising treatment for benign prostatic hyperplasia (BPH), and efficiency of vaporization and hemostasis are both important parameters for such treatment. In this study, we used a high-power laser diode with a wavelength of 980 nm to obtain high vaporization efficiency with good hemostasis. The objective of this study is to evaluate the efficacy of laser vaporization for treatment of BPH in ex vivo experiments using a 300-W high-power laser diode with a wavelength of 980 nm quantitatively.<br>Materials and Methods: An ex vivo experimental setup simulating clinical treatment situation was constructed. Bovine prostate tissue was used as a sample. The power setting was 100, 150, 200, 250, or 300 W, and the irradiation time was 0.5, 1, or 2 s. After laser irradiation, vaporized and coagulated depths were measured.<br>Results: The vaporized depth increased with the laser power and irradiation time, and the results confirmed that the high-power laser diode could efficiently vaporize the prostate tissue. Coagulated depth increased as the laser power became higher.<br>Conclusions: Laser vaporization of prostate tissue using a high-power laser diode with a wavelength of 980 nm represents a promising treatment for BPH; this method exhibits high vaporization efficiency and good hemostasis. However, operators must be aware of the risk of postoperative perforation of the prostatic capsule caused by coagulation of deep regions that cannot be visualized by endoscopic observation.

収録刊行物

• レーザーセラピー

  レーザーセラピー 23 (3), 165-172, 2014

  国際光治療学会

キーワード

• absorption coefficient
• laser surgery
• scattering coefficient
• transurethral vaporization of the prostate

詳細情報

• CRID: 1390282679611076096
• NII論文ID: 130004697086
• DOI: 10.5978/islsm.14-or-12
• ISSN: 18847269
• ISSN: 08985901
• Web Site: https://search.jamas.or.jp/link/ui/2017327147
• 本文言語コード: en
• データソース種別:
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  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可