Hemoperfusion for Hodgkin Lymphoma-associated Hemophagocytic Lymphohistiocytosis
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- Tatara Raine
- Division of Hematology, Jichi Medical University, Japan
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- Sato Makoto
- Division of Hematology, Jichi Medical University, Japan
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- Fujiwara Shin-ichiro
- Division of Hematology, Jichi Medical University, Japan
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- Oh Iekuni
- Division of Hematology, Jichi Medical University, Japan
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- Muroi Kazuo
- Division of Cell Transplantation and Transfusion, Jichi Medical University, Japan
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- Ozawa Keiya
- Division of Hematology, Jichi Medical University, Japan
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- Nagai Tadashi
- Division of Hematology, Jichi Medical University, Japan
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抄録
Hemophagocytic lymphohistiocytosis (HLH), which is associated with various underlying conditions, is characterized by hypercytokinemia. Because it is frequently lethal, immediate mitigation of the hypercytokinemia is vital to save patients, particularly when treatments for the patient's underlying condition are ineffective on HLH. We herein present a case of Hodgkin lymphoma associated with HLH in which the HLH did not improve even after chemotherapy. We attempted to save the patient using hemoperfusion with a polymyxin B-immobilized fiber column to remove cytokines; following this treatment, the patient rapidly recovered. Hemoperfusion may be a strategic method to rescue intractable HLH patients.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 53 (20), 2365-2368, 2014
一般社団法人 日本内科学会
