Lowering Effect of Firefly Squid Powder on Triacylglycerol Content and Glucose-6-Phosphate Dehydrogenase Activity in Rat Liver
-
- Takeuchi Hiroyuki
- Department of Food and Nutrition, Toyama College
-
- Morita Ritsuko
- Department of Food and Nutrition, Toyama College
-
- Shirai Yoko
- National Institute for Materials Science
-
- Nakagawa Yoshihisa
- Food Research Institute, Toyama Prefectural Agricultural, Forestry & Fisheries Research Center
-
- Terashima Teruya
- Food Research Institute, Toyama Prefectural Agricultural, Forestry & Fisheries Research Center
-
- Ushikubo Shun
- Faculty of Agriculture, Kagawa University
-
- Matsuo Tatsuhiro
- Faculty of Agriculture, Kagawa University
この論文をさがす
抄録
Effects of dietary firefly squid on serum and liver lipid levels were investigated. Male Wistar rats were fed a diet containing 5% freeze-dried firefly squid or Japanese flying squid for 2 weeks. There was no significant difference in the liver triacylglycerol level between the control and Japanese flying squid groups, but the rats fed the firefly squid diet had a significantly lower liver triacylglycerol content than those fed the control diet. No significant difference was observed in serum triacylglycerol levels between the control and firefly squid groups. The rats fed the firefly squid had a significantly lower activity of liver glucose-6-phosphate dehydrogenase compared to the rats fed the control diet. There was no significant difference in liver fatty acid synthetase activity among the three groups. Hepatic gene expression and lipogenic enzyme activity were investigated; a DNA microarray showed that the significantly enriched gene ontology category of down-regulated genes in the firefly squid group was “lipid metabolic process”. The firefly squid group had lower mRNA level of glucose-6-phosphate dehydrogenase compared to the controls. These results suggest that an intake of firefly squid decreases hepatic triacylglycerol in rats, and the reduction of mRNA level and enzyme activity of glucose-6-phosphate dehydrogenase might be related to the mechanisms.
収録刊行物
-
- Journal of Oleo Science
-
Journal of Oleo Science 63 (12), 1293-1301, 2014
公益社団法人 日本油化学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390282679069145856
-
- NII論文ID
- 130004704206
-
- NII書誌ID
- AA11503337
-
- ISSN
- 13473352
- 13458957
-
- NDL書誌ID
- 025935951
-
- PubMed
- 25452266
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可