Intraductal papillary mucinous neoplasmを契機に発見されたinvasive micropapillary carcinoma成分をともなった膵癌の1例 A case of invasive micropapillary carcinoma of the pancreas concomitant with intraductal papillary mucinous neoplasm

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著者

    • 田中 宏樹 TANAKA Hiroki
    • JA三重厚生連鈴鹿中央総合病院消化器内科 Department of Gastroenterology, JA Suzuka General Hospital
    • 佐瀬 友博 SASE Tomohiro
    • JA三重厚生連鈴鹿中央総合病院消化器内科 Department of Gastroenterology, JA Suzuka General Hospital
    • 岡野 宏 OKANO Hiroshi
    • JA三重厚生連鈴鹿中央総合病院消化器内科 Department of Gastroenterology, JA Suzuka General Hospital
    • 向 克巳 MUKAI Katsumi
    • JA三重厚生連鈴鹿中央総合病院消化器内科 Department of Gastroenterology, JA Suzuka General Hospital
    • 渡辺 玄 WATANABE Gen
    • 新潟大学大学院医歯学総合研究科分子診断病理学分野 Division of Molecular and Diagnostic Pathology, Graduate School of Medical and Dental Sciences, Niigata University

抄録

77歳女性.膵管内乳頭粘液性腫瘍精査の際に,膵頭部に膵癌を指摘し,外科切除術を施行した.組織学的にinvasive micropapillary carcinoma(IMPC)をともなう管状腺癌と診断した.IMPCは,他臓器では高悪性度病変の指標とされているが,膵臓での報告が少なく,生物学的悪性度や予後は不明である.今回,まれな膵管内乳頭粘液性腫瘍に併存したIMPC膵癌を経験したため,報告する.

Invasive micropapillary carcinoma (IMPC), a rare subtype of adenocarcinoma, has a high incidence of lymph node metastasis and is associated with a poor prognosis. A 77-year-old woman was admitted to our hospital for the assessment of intraductal papillary mucinous neoplasm (IPMN). We diagnosed her with pancreatic cancer concomitant with IPMN and performed pancreaticoduodenectomy. The lesion was predominantly composed of ductal adenocarcinoma with a micropapillary component. On immunohistochemical analysis, a characteristic " inside-out pattern" was observed in the micropapillary component. This confirmed the diagnosis of pancreatic cancer with a micropapillary component. In the present report, we describe a very rare case of IMPC of the pancreas.

収録刊行物

  • 日本消化機病學會雜誌. 乙

    日本消化機病學會雜誌. 乙 111(11), 2149-2156, 2014

    The Japanese Society of Gastroenterology

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