Bilateral Serous Retinal Detachment as a Presenting Sign of Nephrotic Syndrome

  • Izzedine Hassan
    Department of Nephrology, Pitie Salpetriere Hospital, France Department of Nephrology, Park Monceau International Clinic, France
  • Fardeau Christine
    Department of Ophthalmology, Pitie Salpetriere Hospital, France
  • Gauthier Marion
    Department of Nephrology, Pitie Salpetriere Hospital, France
  • Fel Audrey
    Department of Ophthalmology, Pitie Salpetriere Hospital, France
  • Attias Philippe
    Department of Nephrology, Pitie Salpetriere Hospital, France
  • Benabdellah Nawal
    Department of Nephrology, Pitie Salpetriere Hospital, France
  • Sassi Mohamed-Ali
    Department of Ophthalmology, Pitie Salpetriere Hospital, France
  • Bodaghi Bahram
    Department of Ophthalmology, Pitie Salpetriere Hospital, France

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抄録

We herein present a case of bilateral serous retinal detachment (SRD) as a presenting sign of nephrotic syndrome (NS). A 48-year-old man complained of decreased vision related to bilateral SRD. Laboratory tests revealed NS (serum albumin, 17 g/L: proteinuria, 15.40 g over 24 hours). Following treatment for edema with a diuretic, the bilateral SRD resolved completely, with a full recovery of the patient's vision. A kidney biopsy disclosed glomerular and vascular amyloid deposits; the amyloid stained strongly with anti-λ antiserum. Therefore, a diagnosis of AL amyloidosis was made. The sudden appearance of SRD should raise suspicion of a diagnosis of NS. Prompt recognition of this symptom is important for early treatment and restoration of the visual function.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 53 (22), 2609-2613, 2014

    一般社団法人 日本内科学会

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