IgA-dominant Postinfectious Glomerulonephritis Associated with <i>Escherichia coli</i> Infection Caused by Cholangitis
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- Kikuchi Hiroaki
- Department of Nephrology, Yokosuka Kyosai Hospital, Japan
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- Aoyagi Makoto
- Department of Nephrology, Yokosuka Kyosai Hospital, Japan
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- Nagahama Kiyotaka
- Department of Pathology, Yokohama City University, School of Medicine, Japan
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- Yamamura Chisato
- Department of Nephrology, Yokosuka Kyosai Hospital, Japan
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- Arai Yohei
- Department of Nephrology, Yokosuka Kyosai Hospital, Japan
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- Hirasawa Suguru
- Department of Nephrology, Yokosuka Kyosai Hospital, Japan
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- Aki Shota
- Department of Nephrology, Yokosuka Kyosai Hospital, Japan
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- Inaba Naoto
- Department of Nephrology, Yokosuka Kyosai Hospital, Japan
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- Tanaka Hiroyuki
- Department of Nephrology, Yokosuka Kyosai Hospital, Japan
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- Tamura Teiichi
- Department of Nephrology, Yokosuka Kyosai Hospital, Japan
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抄録
A 76-year-old man with a history of type 2 diabetes mellitus was admitted with cholangitis caused by cholangiocarcinoma. Cholangitis with Escherichia coli (E. coli) bacteremia recurred due to the unstable bile drainage. At 1 month after recurrence, rapidly progressive glomerulonephritis with nephrotic syndrome was manifested. Renal biopsy findings were consistent with immunoglobulin A (IgA)-dominant postinfectious glomerulonephritis (PIGN). After ensuring that the recurrent cholangitis was controlled by drainage and antibiotic therapy, oral prednisolone was initiated, and the patient's renal function and proteinuria subsequently gradually improved. This is the first case report of IgA-dominant PIGN associated with cholangitis caused by E. coli infection.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 53 (22), 2619-2624, 2014
一般社団法人 日本内科学会