Spontaneous Regression of Cutaneous Blastic Plasmacytoid Dendritic Cell Neoplasm Followed by Acute Monocytic Leukemia Evolving from Myelodysplastic Syndrome

  • Yasuda Hajime
    Division of Hematology, Department of Medicine, Juntendo University School of Medicine, Japan
  • Takaku Tomoiku
    Division of Hematology, Department of Medicine, Juntendo University School of Medicine, Japan
  • Tomomatsu Junichi
    Division of Hematology, Department of Medicine, Juntendo University School of Medicine, Japan
  • Hosone Masaru
    Department of Pathology, Nippon Medical School, Japan
  • Tanaka Hiroyuki
    Department of Hematology, Matsudo City Hospital, Japan
  • Komatsu Norio
    Division of Hematology, Department of Medicine, Juntendo University School of Medicine, Japan

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抄録

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy arising from plasmacytoid dendritic cell precursors. BPDCN typically manifests in the skin, but it can also evolve into a leukemic form or be complicated by acute myeloid leukemia, some cases with a preceding myelodysplastic syndrome (MDS). We herein report the first case of complete spontaneous regression of cutaneous BPDCN followed by acute monocytic leukemia evolving from MDS. This is also the first reported case of gastric BPDCN invasion.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 53 (23), 2717-2720, 2014

    一般社団法人 日本内科学会

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