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- Jain Parul
- Virology Laboratory, Department of Microbiology, King George's Medical University
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- Jain Amita
- Virology Laboratory, Department of Microbiology, King George's Medical University
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- Kumar Arvind
- Virology Laboratory, Department of Microbiology, King George's Medical University
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- Prakash Shantanu
- Virology Laboratory, Department of Microbiology, King George's Medical University
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- Khan Danish Nasar
- Virology Laboratory, Department of Microbiology, King George's Medical University
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- Singh Kaleshwar Prasad
- Virology Laboratory, Department of Microbiology, King George's Medical University
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- Garg Ravindra Kumar
- Department of Neurology, King George's Medical University
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- Kumar Rashmi
- Department of Paediatrics, King George's Medical University
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- Kumar G. Arun
- Manipal Center for Virus Research, Manipal University
この論文をさがす
抄録
Acute encephalitis syndrome (AES) is a major public health problem in eastern Uttar Pradesh, claiming thousands of lives every year. Here we report the common viral etiologic agents of AES and its epidemiology in the vicinity of Lucknow in Uttar Pradesh, North India. Cerebrospinal fluid (CSF) samples collected from patients with AES, who were referred to a viral diagnostic laboratory from January 2011 to December 2012, were tested for IgM antibodies against Japanese encephalitis virus (JEV), dengue virus (DV), herpes simplex virus (HSV), measles virus, mumps virus, varicella zoster virus (VZV), and enterovirus using commercial enzyme immuno-assays. Of the 1,578 enrolled patients, JEV was the most commonly detected (16.2%), followed by DV (10.8%), HSV (9.3%), measles virus (8.9%), mumps virus (8.7%), VZV (4.4%), and enterovirus (0%). Co-positivity with more than 1 virus was observed in 12 patients. The demographic distribution of patients pertaining to age, sex, and geographic and seasonal variation is discussed. Maximum mortality was caused by JEV infection, while patients with HSV infection had maximum residual neuro-psychiatric disability. JEV and DV are the chief causative agents of AES in North India, although other viruses should also be considered in a differential diagnosis.
収録刊行物
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- Japanese Journal of Infectious Diseases
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Japanese Journal of Infectious Diseases 67 (3), 197-203, 2014
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
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詳細情報 詳細情報について
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- CRID
- 1390001206240925952
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- NII論文ID
- 130004757081
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- NII書誌ID
- AA1132885X
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- ISSN
- 18842836
- 13446304
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- NDL書誌ID
- 025476393
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- PubMed
- 24858609
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
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- 使用不可