書誌事項
- タイトル別名
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- Validation of an Optimal Analysis Method and Reproducibility to Calculate the Heart-to-Mediastinum Ratio and Washout Rate in the Iodine-123-labeled Metaiodobenzylguanidine Myocardial Scintigraphy
- 臨床技術 ¹²³I-MIBG心筋シンチグラフィにおける心縦隔比と洗い出し率の解析方法と再現性の検討
- リンショウ ギジュツ ¹ ² ³ I-MIBG シンキン シンチグラフィ ニ オケル シン ジュウカクヒ ト アライダシ リツ ノ カイセキ ホウホウ ト サイゲンセイ ノ ケントウ
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Purpose: The aim of this study was to investigate an appropriate analysis method and multicenter reproducibility of heart-to-mediastinum ratio (H/M) and washout rate (WR) in iodine-123-labeled metaiodobenzylguanidine (123I-MIBG) myocardial scintigraphy with a phantom. Methods: We evaluated the optimal region of interest (ROI) setting method about the mediastinum and heart by varying the position and shape of the ROI. The mathematical method was changed to a combination of decay time correction (DTC) and background correction (BC). We evaluated the reproducibility of the H/M and WR between institutions. Result: H/M decreased to 23.49% and WR increased to 20.68% by changing the mediastinum ROI position from upper to lower. H/M increased to 26.03% by changing the heart ROI position from base to apex. H/M decreased to 38.36% with BC, and WR was reduced up to 48.51% with DTC. Reproducibility of the H/M and WR between institutions was improved by performing optimization of the ROI setting and unification of the mathematical method. Discussion: The position of the mediastinum ROI should be set on the upper mediastinum. The position of the heart ROI should be set on the apex of the heart. WR should be calculated with DTC and BC. Our results suggest that the reproducibility of the H/M and WR between institutions was improved by performing optimization of the ROI setting and unification of the mathematical method.
収録刊行物
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- 日本放射線技術学会雑誌
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日本放射線技術学会雑誌 70 (12), 1420-1428, 2014
公益社団法人 日本放射線技術学会
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詳細情報 詳細情報について
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- CRID
- 1390001206361444864
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- NII論文ID
- 130004776282
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- NII書誌ID
- AN00197784
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- ISSN
- 18814883
- 03694305
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- NDL書誌ID
- 026001950
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- PubMed
- 25672447
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 使用不可