頸部リンパ節転移より判明した副咽頭間隙発生の非浸潤型多形腺腫由来癌例

• 山原 康平

  京都大学大学院医学研究科耳鼻咽喉科・頭頸部外科 大阪赤十字病院耳鼻咽喉科・頭頸部外科

• 伊藤 壽一

  京都大学大学院医学研究科耳鼻咽喉科・頭頸部外科

• 隈部 洋平

  大阪赤十字病院耳鼻咽喉科・頭頸部外科

• 田中 信三

  大阪赤十字病院耳鼻咽喉科・頭頸部外科

• 平塚 康之

  大阪赤十字病院耳鼻咽喉科・頭頸部外科

• 山田 光一郎

  大阪赤十字病院耳鼻咽喉科・頭頸部外科

• 小山 泰司

  大阪赤十字病院耳鼻咽喉科・頭頸部外科

書誌事項

タイトル別名

• A Case of Intracapsular Carcinoma Ex Pleomorphic Adenoma of the Parapharyngeal Space with Cervical Lymph Node Metastasis
• ケイブ リンパセツ テンイ ヨリ ハンメイ シタ フクイントウ カンゲキ ハッセイ ノ ヒシンジュンガタ タケイセン シュ ユライガンレイ

抄録

Carcinoma ex pleomorphic adenoma is a rare aggressive malignant carcinoma developing in a pre-­exisiting pleomorphic adenoma. Capsular invasion has an oppressive prognosis. On the other hand, intracapsular carcinoma ex pleomorphic adenoma is known to have a benign clinical behavior. We report a rare case of intracapsular carcinoma ex pleomorphic adenoma of a minor salivary gland in the parapharyngeal space revealed by prior cervical lymph node metastasis. A 35-year-old male presented with a month-long history of progressive enlargement of the left cervical mass. We performed a biopsy of the mass and the diagnosis of a metastatic adenocarcinoma of undetermined origin was made. To detect the primary tumor, several investigations were performed using various diagnostic modalities. We found a tumor in the left parapharyngeal space. But, unlike the metastatic cervical lymph node, this tumor showed neither FDG uptake nor enhancement on either CT or MRI. These imaging findings did not favor this tumor as the primary site. We were unable to confirm that the tumor in the parapharyngeal space was the primary carcinoma. We performed a left modified radical neck dissection, removal of the tumor in the parapharyngeal space and hemithyroidectomy of the left lobe. Histological examination revealed that the tumor in the parapharyngeal space was carcinoma ex pleomorphic adenoma. We diagnosed it as the primary carcinoma. Despite the absence of capsular invasion, this case featured high-grade malignancy with cervical lymph metastasis.

収録刊行物

• 耳鼻咽喉科臨床

  耳鼻咽喉科臨床 108 (2), 153-159, 2015

  耳鼻咽喉科臨床学会

キーワード

• intracapsular carcinoma ex pleomorphic adenoma
• parapharyngeal space
• capsular invasion
• cervical lymph metastasis

詳細情報

• CRID: 1390001204272876928
• NII論文ID: 130004827508
• NII書誌ID: AN00107089
• DOI: 10.5631/jibirin.108.153
• ISSN: 18844545
• ISSN: 00326313
• NDL書誌ID: 026070252
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I026070252
• Web Site: https://search.jamas.or.jp/link/ui/2015182590
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可