A Study on Cervical Lymph Node Metastasis from Cancer of Unknown Primary Origin

DOI 参考文献6件
  • Taniyama Takashi
    Department of Otorhinolaryngology, Yamatotakada Municipal Hospital
  • Sugiyama Tomonori
    Department of Head and Neck Otorhinolaryngology, Ise Red Cross Hospital
  • Araki Mamika
    Department of Head and Neck Otorhinolaryngology, Ise Red Cross Hospital
  • Fukukita Kouhei
    Department of Head and Neck Otorhinolaryngology, Ise Red Cross Hospital
  • Yamada Hiroyuki
    Department of Head and Neck Otorhinolaryngology, Ise Red Cross Hospital
  • Hatakeyama Yoshio
    Department of Otorhinolaryngology, Yamatotakada Municipal Hospital
  • Koyama Shinji
    Department of Otorhinolaryngology, Yamatotakada Municipal Hospital
  • Hosoi Hiroshi
    <orgname lang = "en">Department of Otorhinolaryngology Head and Neck Surgery, Nara Medical University

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Between 2002 and 2011, we treated 18 cases of cervical lymph node metastasis from cancer of unknown primary origin. The subjects were 15 men and 3 women, ranging in age from 45 to 83 years (mean: 65.5 years). The histopathological tumor types were squamous cell carcinoma (15 cases), mucoepidermoid carcinoma (1 case), adenocarcinoma (1 case), and undifferentiated carcinoma (1 case). The largest metastatic lymph nodes were located in the upper deep cervical region in 16 cases. For histologic diagnosis of the metastatic lymph nodes, FNAB (fine needle aspiration biopsy) was conducted in 14 cases and open biopsy in 4 cases. Neck dissection was performed in 17 cases, of which 14 also received postoperative radiotherapy. The overall 5-year survival rate in this study was 63.6%. For the control of metastatic lymph nodes and minute tumors at the primary site, combination therapy consisting of neck dissection and chemoradiotherapy is desirable.<br>

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