Task-specific Ionic Liquid-mediated Facile Synthesis of 1,3,5-Triaryltriazines by Cyclotrimerization of Imines and Their Biological Evaluation

• Anshu Dandia

  Center for Advance Studies, Department of Chemistry, University of Rajasthan

• Anuj K Jain

  Center for Advance Studies, Department of Chemistry, University of Rajasthan

• Sonam Sharma

  Center for Advance Studies, Department of Chemistry, University of Rajasthan

抄録

A highly efficient method for the synthesis of fluorinated 1,3,5-triaryltriazine derivatives is developed by the condensation reaction of aromatic amines and formaldehyde followed by spontaneous cyclotrimerization using task-specific 1,1,3,3-tetramethylguanidine trifluoroacetate [TMG][Tfa] ionic liquid as a environmentally benign solvent in excellent yields at room temperature. The synthesized compounds were subjected for in vitro antitubercular activity against Mycobacterium tuberculosis H37Rv strain using the Löwenstein–Jensen medium.

収録刊行物

• Chemistry Letters

  Chemistry Letters 43 (4), 521-523, 2014-04

  Oxford University Press (OUP)

キーワード

• General Chemistry

詳細情報

• CRID: 1360846644035584256
• NII論文ID: 130004868026
• DOI: 10.1246/cl.130839
• ISSN: 13480715
• ISSN: 03667022
• Web Site: https://academic.oup.com/chemlett/article-pdf/43/4/521/55640783/cl.130839.pdf
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