書誌事項
- タイトル別名
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- Anticipatory Nausea among Ambulatory Cancer Patients Receiving Chemotherapy: Associated with Beginning-of-using before and after the New Antiemetic Drugs
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This study investigated the effect of using the neurokinin-1 receptor antagonist and 5-hydroxytryptamine-3 serotonin (5-HT3) receptor antagonists of the second generation on the rate of incidence of anticipatory nausea (AN) and patients' factors among ambulatory cancer patients receiving chemotherapy. <br>Randomly selected patients who received high emetic chemotherapy or moderate emetic chemotherapy were asked to complete the Morrow Assessment of Nausea and Emesis scale, the Hospital Anxiety and Depression Scale, and the European Organization for Research and Treatment of Cancer QLQ-C30 questionnaire. The evaluations were conducted twice (beginning-of-using before and after the new antiemetic drugs [neurokinin-1 receptor antagonist and 5-HT3 receptor antagonist of the third generation]). Complete data were available for 267 subjects (119 before using new antiemetic drugs; 148 after using new antiemetic drugs). A total of 15.1% vs 6.8% of the patients experienced AN before and after using new antiemetic drugs (P < 0.05). After using new antiemetic drugs, patients' global quality of life score was significantly improved. <br>The findings suggest that the rate of incidence of AN in ambulatory cancer patients who receive chemotherapy was reduced by using new antiemetic drugs.
収録刊行物
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- 医療薬学
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医療薬学 40 (3), 165-173, 2014
一般社団法人日本医療薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001204776190848
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- NII論文ID
- 130004894850
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- ISSN
- 18821499
- 1346342X
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可