De novo Crohn's Disease Following Orthotopic Liver Transplantation: A Case Report and Literature Review
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- Naito Takeo
- Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan
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- Shiga Hisashi
- Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan
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- Endo Katsuya
- Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan
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- Kuroha Masatake
- Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan
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- Kakuta Yoichi
- Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan
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- Kinouchi Yoshitaka
- Health Administration Center, Center for the Advancement of Higher Education, Tohoku University, Japan
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- Shimosegawa Tooru
- Division of Gastroenterology, Tohoku University Graduate School of Medicine, Japan
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抄録
The development of de novo Crohn's disease (CD) after orthotopic liver transplantation (OLT) is rare, possibly due to the continuous use of immunosuppressive treatment. Although several cases of CD following OLT have been reported worldwide, there are currently so such cases in Japan. We herein report the case of a patient who newly developed CD after undergoing OLT for congenital biliary atresia. The patient subsequently underwent ileocecal resection and has since maintained clinical remission. This is the first report of this condition in Japan. We also review the literature concerning cases of de novo inflammatory bowel disease (IBD) developing after OLT, and discuss the causes of and role of immunosuppressive agents in treating IBD.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 54 (2), 199-204, 2015
一般社団法人 日本内科学会