良性頭蓋内圧亢進症を呈した特発性自己免疫性溶血性貧血の1例

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タイトル別名
  • A Case of Idiopathic Autoimmune Hemolytic Anemia Associated with Benign Intracranial Hypertension

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抄録

A 32-year-old woman with idiopathic autoimmune hemolytic anemia (IAIHA) was admitted to our hospital in July 1980 because of severe headache and tinnitus. She had been treated with prednisolone until four months before admission. On admission an acute exacerbation of IAIHA was suggested from severe anemia with reticulocytosis, increase in serum indirect bilirubin and lactic dehydrogenase, undetectable haptoglobin and positive Coombs' tests. In addition, marked papilledemas on bilateral ocular fundi were observed. CSF findings were normal except for elevation of the pressure. Other neurological examinations and brain CT scanning showed no abnormalities. These findings indicated benign intracranial hypertension (BIH). Administration of prednisolone resulted in remarkable improvement of both anemia and BIH within three months. Thereafter for three years IAIHA has been in remission and BIH has revealed no recurrence. It is suggested that BIH in the patient might have been caused mainly by withdrawal of steroid and acute exacerbation of IAIHA.

収録刊行物

  • 臨床血液

    臨床血液 25 (4), 575-582, 1984

    一般社団法人 日本血液学会

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