A case of penile necrosis induced by calciphylaxis associated with chronic renal failure, with a review of the literature

• Sasagawa Isoji

  Yamagata Tokushukai Hospital

• Iijima Tatsuo

  Ibaraki Prefectural Central Hospital

• Saito Hitoaki

  Ibaraki Prefectural Central Hospital

• Hoshi Kiyotsugu

  Yamagata Tokushukai Hospital

• Hirose Yuko

  Yamagata Tokushukai Hospital

• Ohta Shoichiro

  Ibaraki Prefectural Central Hospital Kan-Etsu Hospital

抄録

We report a case of penile necrosis induced by calciphylaxis associated with chronic renal failure. Calciphylaxis is a rare but life-threatening phenomenon characterized by deposition of calcium within small- and medium-sized blood vessels, with subsequent thrombosis, cutaneous ischemia and necrosis. It is a known complication of chronic renal disease in patients on hemodialysis. The co-morbidity and mortality associated with this disease are extremely high. Secondary hyperparathyroidism and increased serum calcium phosphate are characteristic and require aggressive medical management. Our review suggests that parathyroidectomy may improve survival and that survival is independent of the type of local treatment for the penile lesions. Recently, aggressive medical control with calcimimetics (e.g. cinacalcet) has been considered for secondary hyperparathyroidism.

収録刊行物

• Microvascular Reviews and Communications

  Microvascular Reviews and Communications 5 (1), 9-11, 2012

  日本微小循環学会

キーワード

• penile necrosis
• calciphylaxis
• calcimimetics

詳細情報

• CRID: 1390282680230722816
• NII論文ID: 130004942921
• DOI: 10.14532/mvrc.5.9
• ISSN: 18805906
• ISSN: 21881707
• Web Site: https://www.jstage.jst.go.jp/article/mvrc/5/1/5_9/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2015047373
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可