糖尿病患者を対象とした下肢動脈血流波形による末梢神経障害の評価

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  • Assessment of Peripheral Neuropathy in Diabetics Using Lower Extremity Arterial Blood-flow Waveforms

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Of the complications of diabetes, peripheral neuropathy occurs relatively early and at a high frequency, and circulatory problems in the lower extremities are largely involved in its onset. We compared blood-flow waveform patterns in the dorsal artery of the foot using motor nerve conduction velocity (MCV) in the deep fibular nerve. A group with no peripheral neuropathy had a significant type I blood-flow waveform pattern while type III and IV blood-flow waveform patterns indicating atherosclerotic changes were not noted. A group with peripheral neuropathy, however, often had patterns from type II to type III, and type IV waveforms indicating the artery was almost occluded were noted in 14% of the group. In the group with no peripheral neuropathy, R-PV was a mean of 0.14±0.03 m/s while in the group with peripheral neuropathy it was a mean of 0.04±0.02 m/s; a significant difference (p<0.05) was noted, and the level was clearly lower in the group with peripheral neuropathy. Blood-flow waveform patterns past type II and a drop in R-PV are considered to be an indicator of peripheral neuropathy in diabetics, and peripheral neuropathy may be assumed on the basis of lower extremity blood-flow waveform patterns as well.

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  • 超音波検査技術

    超音波検査技術 32 (4), 413-417, 2007

    一般社団法人 日本超音波検査学会

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