Biological Features of the Skin of the Pika, <I>Ochotona rufescens rufescens</I>: Histological Structure and Enzymatic Histochemical Reactivity

DOI Web Site Web Site

Bibliographic Information

Other Title
  • ナキウサギ<I>Ochotona rufescens rufescens</I>の皮膚の生物学的特性: 組織構造と酵素組織化学反応
  • ナキウサギOchotona rufescens rufescensの皮膚の生物学的特性--組織構造と酵素組織化学反応〔英文〕
  • ナキウサギ Ochotona rufescens rufescens ノ ヒフ

Search this article

Abstract

To examine the usefulness of the pika, Ochotona rufescens rufescens, as an experimental animal for skin irritability tests, the histological structure and enzymatic histochemical reactivity of pika skin were investigated. The pika had a hair cycle similar to that of the rabbit. The skin and epidermis of the pika trunk were 1.16mm and 29.5μm thick, on the average, respectively. Both of them were the thickest in the dorsal region followed by the interscapular area, while they were the thinnest in the abdominal region. In the epidermis of the pika, the strata corneum, granulosum, spinosum and basale were rather clearly distinguished. The cell arrangement in the stratum basale was more compact than that in the rabbit. Dermal mast cells, which are distributed in the stratum reticulare in rabbits and guinea pigs, were distributed in the stratum papillare right beneath the epidermis. The mast cell of the pika in the TEM images had granules of low electron density and with relatively long microvilli and rather large mitochondria. The activities of the enzymes, SDH, MDH, LDH, βHBDH, αGPDH, ALD, G6PDH and GPR, in the hair follicles and sebaceous glands of the pika were similar to those of the rabbit.

Journal

  • Experimental Animals

    Experimental Animals 36 (2), 125-133, 1987

    Japanese Association for Laboratory Animal Science

Keywords

Details 詳細情報について

Report a problem

Back to top