B型肝炎における急性/慢性の鑑別に関するルミパルスHBcAb-Nの有用性

  • 山田 依里
    金沢医科大学病院中央臨床検査部
  • 馬場 尚志
    金沢医科大学病院中央臨床検査部 金沢医科大学臨床感染症学
  • 吉野 直美
    金沢医科大学病院中央臨床検査部
  • 圓田 兼三
    金沢医科大学病院中央臨床検査部
  • 飯沼 由嗣
    金沢医科大学病院中央臨床検査部 金沢医科大学臨床感染症学

書誌事項

タイトル別名
  • Clinical usefulness of Lumipulse HBcAb-N in discriminating between acute and chronic hepatitis B

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抄録

The management of chronic active hepatitis B is quite different from that for acute infection. We evaluated the clinical usefulness of Lumipulse HBcAb-N, which detects hepatitis B core IgG antibodies, in differentiating between acute and chronic hepatitis B as initial medical testing. Lumipulse HBcAb-N showed a remarkably high antibody titer only in patients with chronic hepatitis although Lumipulse II HBcAb, a conventional reagent, could not provide results to discriminate it from acute infection. Chronic hepatitis was also diagnosed by the trend in the antibody titer by using Lumipulse HBcAb-N; an increasing antibody titer was observed in acute hepatitis although a high titer persisted from the first examination in chronic patients. Our data suggest that Lumipulse HBcAb-N could provide more accurate and useful information for clinicians in assessing the phase of hepatitis B.

収録刊行物

  • 医学検査

    医学検査 63 (1), 64-68, 2014

    一般社団法人 日本臨床衛生検査技師会

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