Communication to the Editor : Oxidative Rearrangement of Cyclobutanone Derived N,O-Ketals Leading to Pyrrolidone Derivatives

• Murai Kenichi

  Graduate School of Pharmaceutical Sciences, Osaka University

• Endo Daisuke

  Graduate School of Pharmaceutical Sciences, Osaka University

• Kawashita Norihito

  Graduate School of Pharmaceutical Sciences, Osaka University Research Institute for Microbial Diseases, Osaka University

• Takagi Tatsuya

  Graduate School of Pharmaceutical Sciences, Osaka University Research Institute for Microbial Diseases, Osaka University

• Fujioka Hiromichi

  Graduate School of Pharmaceutical Sciences, Osaka University

書誌事項

タイトル別名

• Oxidative Rearrangement of Cyclobutanone Derived <i>N</i>,<i>O</i>-Ketals Leading to Pyrrolidone Derivatives

抄録

A halogen-induced oxidative rearrangement of N,O-ketals prepared from cyclobutanones, leading to pyrrolidone derivatives, is developed. The reaction proceeds via an iminium ether intermediate and, depending on the reaction medium, two types of pyrrolidone derivative, containing a halogen atom or hydroxyl group, can be obtained.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 63 (4), 245-247, 2015

  公益社団法人 日本薬学会

キーワード

• rearrangement
• halogen
• oxidation
• <i>N</i>,<i>O</i>-ketal
• pyrrolidone

詳細情報

• CRID: 1390282679153291520
• NII論文ID: 130005061430
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.c14-00856
• ISSN: 13475223
• ISSN: 00092363
• NDL書誌ID: 026283514
• PubMed: 25832019
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I026283514
• Web Site: https://www.jstage.jst.go.jp/article/cpb/63/4/63_c14-00856/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2016001652
• 本文言語コード: en
• データソース種別:
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  • NDL
  • Crossref
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  • KAKEN
• 抄録ライセンスフラグ: 使用不可