Progressive Diffuse Pulmonary Interstitial Opacities due to Complications of Pulmonary Tumor Emboli: An Autopsy Case Report
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- Yoshii Yutaka
- Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Japan
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- Kawabata Yoshinori
- Division of Diagnostic Pathology, Saitama Cardiovascular and Respiratory Center, Japan
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- Takayanagi Noboru
- Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan
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- Araya Jun
- Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Japan
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- Kuwano Kazuyoshi
- Division of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, Japan
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- Sugita Yutaka
- Department of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Japan
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抄録
A 76-year-old man complaining of exertional dyspnea was admitted to our hospital. Chest computed tomography revealed bilateral diffuse ground-glass opacities and small nodules. A transbronchial lung biopsy revealed tumor cell emboli in the pulmonary arteries. The patient was diagnosed with gastric adenocarcinoma using an endoscopic stomach biopsy; however, the interstitial opacities progressively worsened and he died of acute respiratory failure. An autopsy revealed extensive pulmonary tumor embolisms (PTE) with associated ischemic damages, e.g., infarctions, alveolar wall thickening with cuboidal metaplasia, hemorrhage, and diffuse alveolar damage. The ground-glass opacities in the chest computed tomography findings appear to correlate with the pathological ischemic changes associated with PTE.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 54 (8), 955-960, 2015
一般社団法人 日本内科学会