リンパ形質細胞様形態を呈し低悪性度B細胞リンパ腫との鑑別を要したCD20陽性骨髄腫

DOI Web Site PubMed

書誌事項

タイトル別名
  • CD20-positive plasma cell myeloma with lymphoplasmacytoid appearance mimicking low-grade B-cell lymphoma
  • リンパ ケイシツ サイボウ ヨウ ケイタイ オ テイシ テイアクセイド B サイボウ リンパシュ ト ノ カンベツ オ ヨウシタ CD20 ヨウセイ コツズイシュ

この論文をさがす

抄録

CD 20 positive myeloma with small lymphoplasmacytoid morphology is difficult to differentiate from mature B-cell lymphoma. A 71-year-old male was referred to our hospital because of osteolytic vertebral fractures and anemia. Urine was positive for Bence Jones protein, κ type. Bone marrow consisted of approximately 30% small lymphoplasmacytoid cells with scant cytoplasm, and these cells were positive for CD20, CD23 and CD138. FISH analysis revealed t(11;14)(CCND1/IGH). Myeloma with t(11;14) is closely associated with small lymphoplasmacytoid appearance and CD20 and CD23 expressions. The patient was diagnosed as having myeloma based on clinical and cytogenetic findings, and achieved VGPR (very good partial response) after treatment with lenalidomide.

収録刊行物

  • 臨床血液

    臨床血液 56 (3), 335-338, 2015

    一般社団法人 日本血液学会

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ