New Self-Expanding Transcatheter Aortic Valve Device for Transfemoral Implantation : Early Results of the First-in-Asia Implantation of the ACURATE Neo/TF System

• Maeda Koichi

  Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine

• Kuratani Toru

  Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine

• Torikai Kei

  Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine

• Mizote Isamu

  Department of Cardiology, Osaka University Graduate School of Medicine

• Ichibori Yasuhiro

  Department of Cardiology, Osaka University Graduate School of Medicine

• Onishi Toshinari

  Department of Cardiology, Osaka University Graduate School of Medicine

• Nakatani Satoshi

  Department of Cardiology, Osaka University Graduate School of Medicine

• Sakata Yasushi

  Department of Cardiology, Osaka University Graduate School of Medicine

• Toda Koichi

  Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine

• Sawa Yoshiki

  Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine

書誌事項

タイトル別名

• New Self-Expanding Transcatheter Aortic Valve Device for Transfemoral Implantation　– Early Results of the First-in-Asia Implantation of the ACURATE Neo/TF^TM System –

抄録

Background:Feasibility and early results of transfemoral aortic valve implantation using the ACURATE neo/TF^TMself-expanding stent are reported.Methods and Results:The study group of 15 patients (mean age 83.3±6.0) was enrolled with a mean EuroSCORE and STS score of 21.9±11.6% and 7.5±3.1%, respectively. Clinical and echocardiographic evaluations were performed at baseline, discharge, 30 days and 6 months. The primary endpoint was all-cause mortality at 30 days. Transcatheter aortic valve implantation (TAVI) using the ACURATE neo/TF device was successful in 14 patients; 1 patient underwent valve-in-valve implantation because the prosthetic valve embolized during withdrawal of the delivery system. Conversion to surgery, coronary obstruction, peri-operative stroke, and pacemaker implantation did not occur at 30 days. Mean transvalvular gradients at discharge significantly decreased from 44.2±10.5 mmHg (preprocedural) to 7.7±3.1 mmHg (P<0.0001) and effective orifice area significantly increased from 0.77±0.12 to 1.69±0.25 cm²(P<0.0001). None or trace paravalvular leak was revealed in 50.0%, and no patient exhibited moderate or higher paravalvular leak. The overall mortality at 30 days and 6 months was 0% and 6.7%, respectively.Conclusions:A new self-expanding TF TAVI device, ACURATE neo/TF, is safe and effective in the treatment of severe aortic stenosis in elderly patients at high risk for surgery. (Circ J 2015; 79: 1037–1043)

収録刊行物

• Circulation Journal

  Circulation Journal 79 (5), 1037-1043, 2015

  一般社団法人 日本循環器学会

キーワード

• Aortic stenosis
• Japanese
• Valvular disease

詳細情報

• CRID: 1390282680085933824
• NII論文ID: 130005066263
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.cj-14-1110
• ISSN: 13474820
• ISSN: 13469843
• NDL書誌ID: 026342632
• PubMed: 25740501
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I026342632
• Web Site: https://www.jstage.jst.go.jp/article/circj/79/5/79_CJ-14-1110/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2015281971
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
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