Intravascular Hemolytic Anemia in a Patient with Antibodies Related to Meropenem
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- Oka Satoko
- Division of Hematology, Japanese Red Cross Society Wakayama Medical Center, Japan
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- Shiragami Hiroshi
- Division of Hematology, Japanese Red Cross Society Wakayama Medical Center, Japan
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- Nohgawa Masaharu
- Division of Hematology, Japanese Red Cross Society Wakayama Medical Center, Japan
この論文をさがす
抄録
A 76-year-old woman treated with meropenem developed intravascular hemolytic attacks. A direct antiglobulin test was positive for C3d and IgG, and drug-dependent antibody testing indicated that the antibodies were indeed drug-dependent and reacted with drug-treated RBCs and RBCs in the presence of the drug. To our knowledge, this is the first reported case in which the causative antibodies related to meropenem were identified. This case highlights the importance of maintaining a high level of suspicion for drug-induced immune hemolytic anemia in patients with explained hemolysis as well as conducting specialized serologic testing.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 54 (10), 1291-1295, 2015
一般社団法人 日本内科学会
