A case of sinonasal undifferentiated carcinoma successfully treated by etoposide plus cisplatin therapy

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  • Ohba Susumu
    Department of Head and Neck Surgery and Otolaryngology, Saitama Medical University International Medical Center
  • Ohno Tsunehisa
    Department of Otolaryngology, Head and Neck Surgery, Kurashiki Central Hospital
  • Sato Shin-ichi
    Department of Otolaryngology, Head and Neck Surgery, Kurashiki Central Hospital

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  • Etoposide，Cisplatin療法が著効した鼻副鼻腔未分化癌の1例

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Abstract

Sinonasal undifferentiated carcinoma (SNUC) is uncommon, often presents in the advanced stages, and is associated with a poor prognosis. A standardized treatment has yet to be established. We report a patient with SNUC who was successfully treated by etoposide plus cisplatin (EP) therapy.<br>A 35-year-old man who presented with a history of dull headache was diagnosed with SNUC (T4bN0M0). Induction chemotherapy of EP therapy was commenced, resulting in complete remission after one cycle. A further two cycles of EP therapy were undertaken, followed by carbon-ion radiotherapy. There has been no recurrence or metastasis. This case suggests that EP therapy might be an effective treatment for patients with SNUC.

Journal

  • Toukeibu Gan

    Toukeibu Gan 41 (1), 26-29, 2015

    Japan Society for Head and Neck Cancer

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