Initial hemodynamic management of septic shock~where is and how to get the goal ?

DOI
  • Shime Nobuaki
    Emergency & Critical Care Medicine, National Hospital Organization Kyoto Medical Center

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Other Title
  • 敗血症性ショックの初期循環管理~どこをどのようにして目指せばよいのか

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Abstract

Provision of early hemodynamic and oxygen transport resuscitation is one of the key components to improve outcome of the septic shock patients. Since year 2001, importance of achieving a goal in a context of early, quantitative goal-directed therapy(EGDT) has been implicated. Prompt administration of crystalloids such as Ringer's solutions by 30 ml/kg or 2,000 ml, in combination with vasopressors represented by noradrenaline, with referring mean arterial blood pressure and arterial lactate level has been accepted as a useful treatment option. Controversy exists, however, regarding the type of fluids, utilization of universal algorism including other hemodynamic parameters, or vasopressors/inotropes. Avoidance of excess fluid administration is also currently debated. This concise review will discuss current evidence on the aforementioned controversies.

Journal

  • CIRCULATION CONTROL

    CIRCULATION CONTROL 36 (1), 11-17, 2015

    Japan Society of Circulation Control in Medicine

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