LATE BREAKING COHORT STUDY (JCS 2015) : Clinical Presentation, Management and Outcome of Japanese Patients With Acute Myocardial Infarction in the Troponin Era : Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET)
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- Ishihara Masaharu
- Division of Coronary Artery Disease, Department of Internal Medicine, Hyogo College of Medicine
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- Fujino Masashi
- Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
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- Ogawa Hisao
- Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center Department of Cardiovascular Medicine, Graduate School of Medical Science, Kumamoto University
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- Yasuda Satoshi
- Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
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- Noguchi Teruo
- Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
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- Nakao Koichi
- Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center
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- Ozaki Yukio
- Department of Cardiology, Fujita Health University Hospital
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- Kimura Kazuo
- Division of Cardiology, Yokohama City University Medical Center
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- Suwa Satoru
- Department of Cardiology, Juntendo University Shizuoka Hospital
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- Fujimoto Kazuteru
- Department of Cardiology, National Hospital Organization Kumamoto Medical Center
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- Nakama Yasuharu
- Department of Cardiology, Hiroshima City Hospital
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- Morita Takashi
- Division of Cardiology, Osaka General Medical Center
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- Shimizu Wataru
- Division of Cardiology and Regenerative Medicine, Nippon Medical School
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- Saito Yoshihiko
- First Department of Medicine, Nara Medical University
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- Tsujita Kennichi
- Department of Cardiovascular Medicine, Graduate School of Medical Science, Kumamoto University
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- Nishimura Kunihiko
- Department of Preventive Medicine and Epidemiologic Informatics, National Cerebral and Cardiovascular Center
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- Miyamoto Yoshihiro
- Department of Preventive Medicine and Epidemiologic Informatics, National Cerebral and Cardiovascular Center
書誌事項
- タイトル別名
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- Clinical Presentation, Management and Outcome of Japanese Patients With Acute Myocardial Infarction in the Troponin Era – Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET) –
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Background:New criteria for diagnosis of acute myocardial infarction (AMI) were proposed in 2000 as a universal definition, in which cardiac troponin (cTn) was the preferred biomarker. A large number of patients formerly classified by creatine kinase (CK) as unstable angina are now ruled-in by cTn as non-ST-elevation myocardial infarction (NSTEMI).Methods and Results:The Japanese registry of acute Myocardial INfarction diagnosed by Universal dEfiniTion (J-MINUET) is a prospective and multicenter registry conducted in 28 institutions. We enrolled 3,283 consecutive patients with AMI diagnosed by cTn-based criteria who were admitted to participating institutions within 48 h of symptom onset. There were 2,262 patients (68.9%) with STEMI and 1,021 (31.1%) with NSTEMI. CK was not elevated more than twice the upper limit of normal in 458 patients (44.9%) with NSTEMI (NSTEMI-CK). Although there was no significant difference in the in-hospital mortality of STEMI and NSTEMI with CK elevation (NSTEMI+CK) patients (7.1% vs. 7.8%, P=0.57), it was significantly lower in patients with NSTEMI-CK than in those with STEMI or NSTEMI+CK (1.7%, P<0.001 for each).Conclusions:J-MINUET revealed the clinical presentation, management and outcomes of Japanese patients with AMI in the current cTn era. We should be aware of the difference between AMI diagnosed by CK-based criteria and AMI diagnosed by cTn-based criteria when using universal definitions for the diagnosis of AMI. (Circ J 2015; 79: 1255–1262)
収録刊行物
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- Circulation Journal
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Circulation Journal 79 (6), 1255-1262, 2015
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390282680082983552
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- NII論文ID
- 130005073152
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 026398663
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- PubMed
- 25912696
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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