A case of drug-induced liver injury caused by Keishi-karyukotsu-boreito and Shin-i-seihaito

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  • 桂枝加竜骨牡蛎湯,辛夷清肺湯による薬物性肝障害の1例

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Abstract

A 43-year-old woman was admitted to our hospital due to liver dysfunction. She had a history of liver injury induced by the herbal medicine Keishi-karyukotsu-boreito, which occurred at the age of 35 years. On the present occasion, she had taken the herbal medicine Shin-i-seihaito to treat her sinusitis for one month. We diagnosed liver injury caused by Shin-i-seihaito, and her liver dysfunction normalized after discontinuation of Shin-i-seihaito. This is the first reported case of drug-induced liver injury caused by the herbal medicines Keishi-karyukotsu-boreito and Shin-i-seihaito.

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